Tretinoin is the acid form of vitamin A and so also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel.

Tretinoin is most commonly used as a form of acne treatment. It was the first retinoid developed for this type of topical use. It is used by some as a hair loss treatment and also a component of many commercial products that are advertised as being able to slow skin aging or remove wrinkles. Topical tretinoin is also used to treat and reduce the appearance of stretch marks by increasing collagen production in the dermis.

Tretinoin is a safe and effective topical treatment premature aging of the skin. Tretinoin has been proven to improved mild sun damage, fine wrinkles and discoloration if used as part of with a comprehensive skin care program.

How does tretinoin work?

Looking and feeling young have always been important to most people. As the median age of our population rises, more and more people are searching for safe and effective ways to reduce the signs of aging. Over the past ten years, many new techniques for combating the signs of aging have become available. Print and broadcast media inundated consumers with advertising about quick and easy cures for aging skin that promise dramatic results overnight. How can you decide what treatment is the best for you?


First, let's look at how and why skin ages. Skin becomes thinner and less able to hold moisture over time. Elasticity decreases as collagen and elastin are damaged by time and sunlight. Skin becomes hyperpigmented. Facial muscles atrophy and become somewhat contracted, contributing to wrinkles. Some of the major causes of premature skin aging are excessive sun exposure, smoking, poor nutrition and lack of skin care.


Topical medications, Botox, laser resurfacing, dermabrasion and chemical peels are some of the more common techniques offered to reduce skin damage associated with aging. Botox works to temporarily paralyze the small smooth muscles of the face. Injections cost about $400-500. A couple of injections are usually needed. Results last about six months. Chemical peels use acids to destroy the uppermost layer of damaged skin and expose the fresher deep layers. They cab cost between $1000-2000 per treatment. Dermabrasion is a mechanical method of removing the topical damaged skin. The average cost is about $1400. Many of these procedures are costly, painful and have some associated risks.


Use of topical medications can be a less invasive, low risk treatment for sun damaged skin. Tretinoin is topical medication commonly known as Retin-A. The FDA approved tretinoin 1971 for the treatment of acne vulgaris (severe cystic acne).


Tretinoin is a derivative of vitamin A. It works to alter the skin cells by modulating gene expression, rather than inducing cell necrosis (death). The effect of tretinoin is the speeding of skin cell turnover, reducing breakouts and producing smoother, younger looking skin. Melanocytes, the skin cells responsible for skin pigment, are suppressed by tretinoin. This decreases skin discoloration and uneven skin tone. As a result, fine lines and wrinkles are reduced, skin feels smoother and looks more evenly colored.


While many people know Retin-A for its effectiveness in the treatment of severe acne, other uses have been found. It is important to understand what this medication can and cannot do for your skin. Tretinoin cannot reverse severe skin damage, wrinkling or advanced sun damage.

APPLICATION:
Retin-A Help
Here are some guidelines that may make it easier to take this great medicine.

*Apply Retin-A in a thin layer at night. A small amount goes a long way.

*In the morning wash your face with a mild facial scrub or rough wash cloth. This will help reduce the noticeable flaking.

*After washing, apply a good water-based moisturizer. Yes, guys, this applies to you too. The moisturizer will make the drying effect of the medicine more tolerable.

*If flaking occurs during the day use a wash cloth to remove it and apply more moisturizer, or just apply moisturizer.

*Try using a moisturizer that also contains a sunscreen. If not, apply sunscreen anytime you are in the sun even for a short amount of time.

*Tretinoin makes you more susceptible to sunburn.

*When you first start using Retin-A, apply it every other night or every 3rd night.

*The flaking and irritation side effects are usually the worst in the first 2 weeks of application. As your skin adjusts to the medicine, you can apply it more frequently.

*If you notice an increase in the irritation or flaking, it's ok to take a break for a couple of days.

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